Toxicology

The following adverse effects were identified: hepatotoxicity, changes in lipid metabolism and in bone density, and teratogenicity.

Learning Goal: I’m working on a toxicology exercise and need a sample draft to help me learn. Acute toxicity: 55 male and 55 female Sprague-Dawley rats were administered does orally at levels of 3160–8250 mg/kg bw. Body weights were determined on regular intervals and animal were observed on regular intervals for treatment related effects, including …

The following adverse effects were identified: hepatotoxicity, changes in
lipid metabolism and in bone density, and teratogenicity.
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Discuss the differences you find with references and the appropriate literature.

Learning Goal: I’m working on a toxicology report and need an explanation and answer to help me learn. Review the evidence of harm resulting from exposure to DPM, using both human and animal studies to consider the dose effect/ response relationship (at least 4 journal articles are required). Ascertain the threshold of harm for DPM …

Discuss the differences you find with references and the appropriate literature. Read More »

Discuss the toxicology of dpm as per the following headings: a. absorption, b. distribution in the body and target organs, c. pathways for biotransformation, d. mechanisms of harm (interaction with cells and tissues)

Learning Goal: I’m working on a toxicology question and need an explanation and answer to help me learn. Discuss the toxicology of DPM as per the following headings: a. absorption, b. distribution in the body and target organs, c. pathways for biotransformation, d. mechanisms of harm (interaction with cells and tissues) e. pathways of elimination …

Discuss the toxicology of dpm as per the following headings:
a. absorption,
b. distribution in the body and target organs,
c. pathways for biotransformation,
d. mechanisms of harm (interaction with cells and tissues)
Read More »